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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

至少在城市大部分人能去上班是不可能的,这将影响多个行业,包括金融、广告、医疗保健和艺术。近两天城市的交通线路、桥梁、隧道都瘫痪了,在最新的报告中,地铁到下周可能会正常运作。
埃尔·南德斯

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

unique
6. 《出租车》(Taxi),导演贾法·帕纳西(Jafar Panahi)。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 长春警方立案调查长生生物
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 十三五规划不再投入LED行业补贴
Open Access Perspective

Soft matter science and the COVID-19 pandemic

9. 2012年搞笑诺贝尔奖之解剖学奖

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

4. Slacking at school

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

This story pulls directly from the real Bling Ring gang , whose burglaries racked up $3 million over the span of ten months in 2008. All of the celebrities listed in the movie were real victims of this group, who claim to have been motivated by the "cultural obsession" surrounding celebrities' personal lives. Whatever their motives, the Bling Ring is a good reminder to take a step back from the media every once in a while.
“尽管这两位研究人员彼此独立工作,但夏普利的基本理论和罗斯的实证调查、实验和实用的设计相结合,产生了一个蓬勃发展的研究领域,并改善了很多市场的功能,”皇家研究院说。
pr(iHbd+xg|gPd&q+&+Y
印度梅加拉亚邦——《孤独星球》上说:“梅加拉亚邦这种平静的状态不会维持太久的,在寻求刺激的人群占领卡西山之前赶紧去那里吧!”照片上拍摄的是乞拉朋齐瀑布,它是印度最高的飞瀑,高达340米。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

But as Western manufacturing and industry have declined, taking many working-class towns with them, parents and grandparents have found that the opportunities they once had are unavailable to the next generation.
在观影从始至终,我都在问自己一个问题:这部电影到底在讲什么……这部电影的主题仿佛一锅杂烩,并不明晰。我希望制片人也在问同样的问题。
n. 设计者
1999年中国航空工业第一、第二集团公司(之后两者合并为中国航空工业集团公司)的成立标志着中国开始进军商业航天领域,显示了中国迈向这一行业的绝心与意志。但实现这一雄心的脚步并不那么平坦。20年之后毫无疑问中国已经成为了大型商用航天领域的成熟玩家,将其他几国远远甩在身后,并有望打破空客和波音的长期垄断。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The survey is based on costs of over 160 items ranging from food and clothing, to domestic help, transport and utilities.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The world’s 100 biggest brands still command a significant premium over others and that value increased by 3 per cent to $3.4tn this year, according to the latest BrandZ rankings compiled by Millward Brown, the research agency.
6. statuesque / a . 高大匀称的,体态优美的。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Emissions have been falling gradually in recent years in most of the developed countries, in part because of economic weakness but also because of strengthening climate policies. Emissions in the 28-nation European Union fell 1.8 percent in 2013, despite increases in coal consumption in a few countries, including Germany and Poland. Emissions decreased sharply in Britain, Italy and Spain.
第一种看法是,油价本质上具有周期性。下跌之后必然会回升。这道波谷越深,下一个山峰就越高。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

[faun'dein]
Prices at China's factory gates fell for a 34th consecutive month in December, pushed down by falling energy and commodity prices.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Chinese Premier Li Keqiang delivers a government work report during the opening meeting of the fourth session of the 12th National People's Congress at the Great Hall of the People in Beijing, capital of China, Mar 5, 2016.
That was in line with last month’s manufacturing PMIs, which showed an uptick in sector activity,
达洛伊西奥的父母从澳大利亚搬到英国,他的父亲卢(Lou)曾在英国石油(BP)和摩根士丹利(Morgan Stanley)工作,而母亲戴安娜(Diana)是一位企业律师,同时也是儿子的合同代表。他们向来都知道达洛伊西奥是一个非常好学的孩子。但戴安娜说因为他是长子,他们本以为他不会做出什么超出寻常的事情来(达洛伊西奥有一个14岁的弟弟)。他们强调,尽管达洛伊西奥成就非凡,尽管他聊天时会聊起马尔科夫模型(Markov models)和随机过程(stochastic processes),他仍只是一个再普通不过的孩子。戴安娜说,他周末仍要出去玩,仍要去参加派对。他还有个女朋友。17岁孩子会做的事情,他都会做。
Bryant is the first player this season with four or fewer points on 14 or more field goal attempts.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

5.生物医学工程师

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 上半年楼市四大动向引人注目
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

I empathize with the Mavs' position. It's tough to tell your fans that all hope is lost in November, and it's especially tough when you've got a Hall of Famer still on your roster.
与此同时,中国12月消费者物价指数(CPI)略升至1.5%,11月为1.4%,为5年低点。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

3.50 First Dates

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Edgar Wright’s Baby Driver is one of the most entertaining thrill rides of this year, this decade. This century.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Two against-the-clock tours of Los Angeles. Two celebrations of the sometimes prickly solidarity among women. Four tremendous performances, from Kitana Kiki Rodriguez, Mya Taylor, Julia Garner and the great Lily Tomlin. “Grandma” is the work of a studio veteran. “Tangerine” was shot on iPhones. Anyone prone to lamenting the death of movies needs to shut up and watch these.
4. How to draw manga
玛丽亚里奥斯
9.Beating Hearts Created In A Petri Dish

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 不只30城!楼市专项治理行动扩围
Review Article

Influenza neuraminidase: A druggable target for natural products

本田已在美国召回了1000多万辆汽车,修复其安全气囊一项潜在的致命缺陷。这种气囊由日本供应商高田公司制造,其充气装置在发生车祸时会突然爆裂,溅出金属碎片伤及乘客。本田已确认有三起死亡和48起受伤事件与这一问题有关。
With the momentum now back behind the iPhone and anticipation growing for the Watch, Mr Cook seems to have won back the confidence of Apple employees, something that analysts say was obvious in his demeanour at this year’s product launches.
"Look What You Made Me Do" is one for the history books, and pop scholars will likely debate for generations whether it was a brilliant P.R. coup or not.
答:写轻小说的时候,我大部分时候都是独自创作。但是写动画的话,就有会导演,有工作人员,他们会对我的作品提出观点。关于分镜往往会有好几次修订。有趣的是那些回馈回来的东西。这是工作中非常有趣的一部分。
无论是从教学还是从研究方面来说,金融课程都是北方高等商学院的核心优势之一。该学院在2001年成立了Edhec-Risk Institute,从事资产和风险管理等领域的研究并发表相关成果。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

黄金市场可能会对美元以及美国加息的前景着迷。但还有一个因素正在逼近:金矿供应下降。
Belmonte's 1950 ticket will be displayed at a Zurich museum that is set to open in 2015, according to Jerome Valcke, FIFA's secretary general. "This is something rare we would like to have for the museum," he said.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

'She does wear wigs and crowns and fancy dresses but I don't give her spray tans or cake her in makeup - I'll wait until she's about five for that.'

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

圣安东尼奥-委内瑞拉塔奇拉州(美联社)--周末,超过100000名委内瑞拉人到哥伦比亚寻找国内短缺的食物和药品,他们中有些人连夜驱车跟着商队前去。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

5. 艾玛?斯通
The committee *bestowed the award upon Yoshinori Ohsumi of the Tokyo Institute of Technology, for his research on *autophagy, which is a self-eating process seen in cells.
新晋的富翁包括第一位以戏剧制作人身份进入榜单的卡梅隆·麦金托什,WeWork的亚当·诺依曼和米格尔·麦凯尔维,以及图片分享网站Pinterest的创始人本·希伯尔曼和埃文·夏普。
2. Google Docs

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 2018年北京GDP首破3万亿
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

n. 慈善,慈善机关(团体), 仁慈,宽厚
《王冠》
Song “Chang’er”(Li Yugang and three Chinese astronauts)
1.摄影:增长了22.3%

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

爱你的老公!
不要在月薪上撒谎。即使你的上任老板没告诉我们(大多数情况都是这样),我们还是会弄清楚的。我还因此开除掉两名员工。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Many grand and spectacular museums are located in picturesque cities like Bruges, Antwerp and Brussels. Art lovers can fully engage themselves in the numerous treasures dating back to the medieval period. Exploring the quiet towns and appreciating their Gothic architecture is also an opportunity not to be missed. As the hometown of the world’s best beers, chocolates and fries, everyone can be a gourmet here. With the 100th anniversary of the outbreak of World War I approaching, Belgium is set to draw many tourists in the coming years.
'People in the community are affected by what I write, ' he says.
According to a research report on 2016 graduates released by 51job.com, a leading job hunting platform in China, 52.11% of college graduates found employment or started their own business.
adj. 高品质的
Look no further than the title sponsor on their building—Smoothie King, a regional drink shop—to realize that the Pelicans have a serious relevancy problem. (By contrast, the NFL's Saints play in the Mercedes-Benz Superdome next door.)

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 家纺行业挤泡沫 企业扩张放缓
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

胡润在接受路透社采访时表示:“这是一种新型的财富创造方式。”他还表示,中国经济正在缓慢下行,中国必须适应这种方式。
据预测,在大宗商品价格上涨和需求温和上升的推动下,2017年以美元计的新兴市场国家出口额将出现自2014年以来的首次增长。
Four government agencies including the commerce ministry and the central bank said in December they would apply tighter scrutiny to "irrational" outbound deals including real estate, hotels, movie theatres, entertainment assets and sports clubs.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Rounding out the top three is Chrissy Teigen, 31, who joins the list for the first time after raking in $13.5 million over the past 12 month-period.
贷款的条件不仅仅只局限于裸照。同样被泄露的还有大量疑似借贷双方对话的屏幕截图,一个贷款人要求女学生提供自己的自慰视频。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

So far this year, companies have announced 376 share-repurchase initiatives for a total of $261 billion, according to data from Birinyi Associates. That's nearly 72% higher than 2012, though slightly lower when compared to the same period in 2013, which was a record year for buybacks.
slew
我们希望看到的亚太地区是一个稳定、有秩序的地区,是一个可以协商一致、达成原则的地区,是一个有能力管控分歧的地区,也是一个有智慧解决争端的地区。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

然而,还有人认为医生的所作所为可能是受不公平的体制所迫。另一位网友称:“作为一个病人,我更关心他们能否治好我的病,而不是他们发表了多少论文。”
2010年中国的房价将达到顶点?
排名:第一

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Martha Cherry took a cigarette out of her mouth, murmured, "I've been there," and resumed smoking. Marc was in shock (which, let's face it, is a pretty healthy response when you realize your own mother may or may not have had thoughts of murdering you while you bathed). He realized for the first time how desperate and lonely it could be to be a housewife. He realized then and there that he was upon a very good idea for a TV show. This conversation was the birth of Desperate Housewives.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

《华胥引》的故事是这样的:卫国公主以身殉国,不久死而复生,从此她改名换姓开始了新的旅程。电视剧改编自唐七公子的同名网络小说,于2015年七月首播,主演林源、郑嘉颖。不过和同类剧集相比,《华胥引》的人气就没那么高了。据网上的评论说,这部戏的主角和服装都不够抓眼。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

《雷神3:诸神黄昏》的搞笑程度远远超出你的想象。这都要感谢杰夫?戈德布卢姆与塔伊加?维迪提两位天才的合作。维迪提不仅是本片导演,他还在电影中饰演了一个极其真诚的石头人战士Korg。
This changed two years ago, though, when Tsinghua University broke into the top 20 for the first time, ranking 18th in 2016. Last year, Peking University joined it in the top 20.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

The study relied on a dataset of hundreds of millions of secret answers and millions of account recovery requests.
时间:2009-10-26 编辑:vicki
时间:2010-05-31 编辑:francie
欧洲工商管理学院(Insead)领衔2017年英国《金融时报》全球MBA百强榜。这是这所拥有多个校区的国际商学院连续第二年高居榜首,去年该学院首次摘得桂冠。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

尽管有少数人坚持这种说法,但绝大多数研究气候的科学家表示,地球正在经历一个长期变暖的趋势,这种趋势给人类带来深刻的威胁,而且几乎完全是由人类活动造成的。
单词democratic 联想记忆:

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Domain name registrar GoDaddy, which is based in Scottsdale, Ariz., broke ground in May on its new Global Technology Center in Tempe. GoDaddy already employs 2, 600 people in the Greater Phoenix area and the new facility is expected to add 300 more. Other companies expanding in Arizona include Asurion, a leader in technology protection services. They opened a new technical support center in Phoenix and want to fill 500 jobs by the end of the year. Energy provider Direct Energy opened a new call center in Tempe this year and is looking to fill as many as 300 openings.
与官方PMI指数相比,财新赞助的系列调查的样本是数目少得多的民营企业,其结果的波动性往往更大。而官方PMI指数则主要关注规模更大的国有企业。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

transport(n /v 运输;狂喜),trans转移,port搬运

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

traditional
Lana Del Rey, 'Lust for Life'
The BFC's news has been met with support from people on social media, who have applauded the designers choosing to forgo the use of animal fur.
在毕业3年后的学员当中,男女毕业生薪资分别为9万美元和7.3万美元,相差近22%。刚完成学业时的男女毕业生薪资差距为17%,因此男女薪资差距随着时间推移而扩大(见图表)。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

1. Apple
But the carriers are having a more difficult time over the winter holidays. About 30 percent of winter holiday flights were delayed in 2012, on top of significant delays in 2011 and 2010. You can check holiday flight statistics from the Transportation Department on its website.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

[?.s?usi'ein]
Remember, no one is ever perfectly prepared for every situation. You’ve probably discovered this by now. Your education gave you a foundation for the job, but growth happens in the trenches. Maybe you motivated your team not just to meet the new deadline, but to deliver extraordinary work. Perhaps you realized you had more poise than you ever expected in a client situation. Or, you suddenly discovered that you can capitalize on the relationships you’ve built and become a “rainmaker” for your organization. Before you can learn any of these things, you have to learn to say “Yes.” It’s okay to acknowledge the butterflies in your stomach; however, it’s not okay to let them stifle your growth.
数百所国内高校的2017届、2015届和2013届毕业生、共281万人参与了这项调查。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

China's economic performance in the past few years should suffice to put predictions of a hard landing to a full stop. China's economy will continue to enjoy medium-high growth and be upgraded to higher levels
《美国队长3:内战》将于2016年5月6日在各大影院上映。美国队长与钢铁侠开战,你支持谁?
恩爱日新。即便没有一切,只要有爱便足矣。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

A total of 16 Chinese companies are in the top 100 on the list, including China Mobile, Alibaba and Tencent.
他说,到1997-98年亚洲金融危机爆发时,美联储的回应已变得更加迅速,它退出了紧缩周期,担心东南亚的动荡会影响美国经济。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 2018年我国城镇新增就业1361万人
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

It has now entered the top 20 for the first time.
学会控制自己的情绪,控制自己的想法,克服对被拒绝的恐惧,学会向别人敞开心扉。
Under the Skin is just so visually free and uninhibited that there is an intense dark, destructive sexiness in everything about it – quite apart from the hilarious, bizarre, mesmeric eroticism of the film itself. It is a work of subcutaneous potency. It gets under your skin.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

《火星救援》获评喜剧/音乐类最佳影片。
Once Upon A Time

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 燕郊二手房单价普降万元
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Except your Watson, he thinks it's hot.
9) Well Done: It’s a cliché, no doubt. Sometimes, it isn’t enough just to say thanks. People want to know what they did was great and why. They pour so much sweat and soul into their projects.They need to know their work was special and had meaning to someone.
同样,A型与B型人格理论指出,B型人与A型人截然相反。根据定义,B型人格的人生活压力较小。尽管他们在没有实现自己的目标时更容易忽视身体或精神上的压力,但通常可以稳定工作,享受成功。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 二线城市是2016年楼市主攻阵营
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

The hair creates a resemblance to the look of Michelle Pfeiffer, but Ms. Chastain gives it more of an edge. Kay Georgiou, who frequently styles the hair of Matt Damon and Gwyneth Paltrow for films, oversaw the look.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 环保风暴过后 三亚6项目整改
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

报道称,代理商和投资机构正纷纷涌入该行业,对世界上第二大经济体的平台造成了额外改变。
6、《招魂2:恩菲德的骚灵》

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

梅根·马克尔
The cities of Hefei and Xiamen once again led the pack with growth of 48.6 per cent and 45.9 per cent, respectively.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

bene好,fit做-做事后的好处
China does not want to resort to yuan depreciation to boost exports as that would dampen the restructuring and upgrading of the corporate sector.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Detroit Three: The other two Michigan-based manufacturers still face bumps. General Motors copes with continued fallout from its ignition switch recall while Ford fights through the most aggressive launch period in the company’s history.
As the new iPhone continues to smash its own launch records, Mr Cook has unveiled products such as Apple Watch and Apple Pay that take the iPhone maker into the realms of fashion and finance, recapturing a spirit of innovation that many feared had died with Jobs. In the process, Apple’s valuation this year has grown by almost as much as Google’s entire market capitalisation.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 广州“自愿不购买社保”条款无效
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The QUBE will remind you to recycle, monitor when the trash was last taken out, and tell you to change the air freshener. These are all things people usually remember to do anyway, by the smell and all, but now there's a $300 "elegant" stainless steel can that'll constantly remind you with annoying mobile alerts.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

大隅在自噬作用上的研究成果,为帕金森病、糖尿病等常见疾病的治疗带来了一线希望。
《风骚律师》(Better Call Saul),AMC,2月8日播出。这是文斯·吉里根(Vice Gilligan)与彼得·古尔德(Peter Gould)的《绝命毒师》的衍生剧,或许是今年冬天最受期待的新剧了。鲍勃·奥登科克(Bob Odenkirk)饰演狡猾的律师索尔·古德曼(Saul Goodman),剧情设定在《绝命毒师》的故事发生之前,所以布莱恩·克莱斯顿(Bryan Cranston)或亚伦·保罗(Aaron Paul)至多只是客串出演而已。但观众们最喜欢的乔纳森·班克斯(Jonathan Banks)将在里面重现他在《绝命毒师》中的角色——冷静的行动执行者迈克·厄尔曼特劳特(Mike Ehrmantraut)。
但3D版吉祥猴的形象却未能避开炮击,挑剔的网友纷纷吐槽:“这让我想起红绿灯!”;“水墨画的精髓全然不见”;“耳朵下面的两个球是什么呀,太抢镜了……”;“已被它丑哭。”
我们要求FlightAware对航班抵达延误情况进行统计,而不是航班出发延误情况,因为有时候,航空公司可以让飞机在空中飞行期间追回地面上失去的时间。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

As a measure of that fall, 10 works have sold at auction for more than $100 million since 2004, and all of them were made by modern or contemporary artists in the past 120 years. Older paintings have seen their value, in relative terms, level off or decline. The trend was plain to see in recent weeks, as London’s auction houses tried to find buyers for their latest tranche of old masters. As has been the case in recent years, there were few works by major names.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

排放量去年的增幅比过去十年中2.5%的平均增长率略低,而且排放量增幅之所以下降,很大程度上是由中国经济增长放缓所引起的。中国是世界上最大的温室气体排放国。可能还需要再花一到两年时间,才能弄清楚中国排放量的增长究竟有没有放缓,还是最近数年那种极高的增速仍会持续。
The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
课程安排:周五周六交替上课,入学伊始学员需参加一个为期一周的会议,还有一个为期一周的国际学习研讨会

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

只有两个人知道奥斯卡奖获奖名单,他们负责审计整个流程,这两个人就是PwC公司的税务顾问玛莎?瑞兹和会计师布莱恩?卡利南。
It set minimum prices too high for commodities including cotton, sugar and corn, and as those prices diverged from the market prices, authorities encouraged excessive production as well as strong import flows.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: “房住不炒”从此深入人心
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Cheng further says, "once you find a list that fits your needs, just tap on the list to see suggested locations. Then swipe right or left to see more options and tap 'read more' or the arrow at the bottom of the screen to select a venue and get more details.".
rid笑+ic+ulous多…的→多笑的→可笑的

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

这些新数据是由一个叫做全球碳计划(Global Carbon Project)的追踪项目提交的,发表在了期刊《自然·地球科学》(Nature Geoscience)上。数据公布之际,正是联合国(United Nations)一次峰会召开前夕。此次峰会意在激发新的政治愿望来解决气候变化问题。科学家说,这些数据表明,如果要把长期的全球变暖问题控制在可以承受的范围内,还需要做出极大的努力。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

“A worker sent a text to a colleague saying he was quitting and asked her to forward it to management.”
中国在朝鲜半岛问题上的立场是明确的、一贯的,坚持实现半岛无核化,坚持维护半岛的和平稳定,坚持通过对话协商解决问题。
这位工作人员说道:“她注册时说自己姓韩,也不是像媒体上报道的姓苏。”

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

pilot
We will promote a steady increase in consumer spending.
Economists had forecast a 1.5 per cent annual rate, after a 1.6 per cent reading in September. Beijing's inflation target is "around 3 per cent" this year.
6. Our last universal common ancestor gets a makeover

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

伦敦商学院在所有这5项排名上表现强劲。其所有课程都跻身欧洲前十,包括全日制MBA课程排名第二,合办EMBA(与美国哥伦比亚商学院(Columbia Business School)合办)和定制高管教育课程均排名第四。
Guangdong has cemented its position as the country's largest provincial economy for the 28th consecutive year, with its gross domestic product (GDP) exceeding 7.9 trillion yuan in 2016.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

[pr?'d?ktiv]
5.英国人设定的“狗狗奖”
报告指出,济南位列榜首的部分原因是该市在进行大规模基础设施建设,如修建地铁和旨在优化雨水利用的其他工程。哈尔滨高峰时段严重拥堵则更多是因为城市规划不合理。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Cliff Stevenson, an anti-dumping expert who publishes the report based on data filed with the WTO, said the surge in US cases was driven largely by the steel industry. The increase also represented the range of countries from China to Australia, the UK and the Netherlands against which US companies were willing to file anti-dumping complaints.
Many believe the population is no longer a major threat to China's resources and environment. Instead, China's population challenges have shifted to low birth rates, an aging society and a widening gender imbalance. China has already experienced a shortage of skilled workers in places like the Pearl River Delta, so it might not be long before we see major reforms.

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